Prenatal diagnostics

A couple faces a difficult decision when a nuchal translucency test returns a high result for chromosomal abnormality

Jane, a 35-year-old primigravida, presented at 7 weeks, 5 days' gestation.

She had no significant medical/surgical past history and a regular, 28-day menstrual cycle.

She was not on any medications, and had no known allergies. Routine antenatal investigations were unremarkable.