Weight off the mind

Kate is a 44-year-old stay-at-home mother, married with an 11-year-old daughter.

Kate has depression (treated with amitriptyline), obesity and impaired glucose tolerance. 

She reports regularly binging on high-calorie, high-sugar foods with consequent feelings of guilt. Kate currently weighs 95kg and reports a 10kg gain in the past 12 months. 

Antidepressants and weight gain

Tricyclic antidepressants and monoamine oxidase inhibitors are more commonly associated with weight gain than SSRIs. 

Studies have shown a typical gain of up to 1.5kg a month while on amitriptyline. One of the main reasons for this is an increase in appetite, with reported cravings particularly for high-carbohydrate, high-sugar foods. 

Kate's typical daily intake