Why aren’t these antibiotics working?

A middle-aged construction worker’s cellulitis does not respond to oral or intravenous antibiotics

Eric, 42, was sent to the ED by his GP because his lower limb cellulitis was not responding to oral cephalexin.


He had presented to his GP three days earlier with redness, swelling and pain of the left leg. He was on a statin for hypercholesterolaemia, but had no other past medical history of note.

Two weeks prior, the patient, a construction labourer, had dropped a bag of concrete on his leg, leaving a small graze over the tibia.

A shallow ulcer slowly developed at the site of the graze. Erythema