CPD

• Epstein-Barr virus (EBV) is a human herpesvirus that persists lifelong in host B-lymphocytes in a ‘latent’ state.
• The viral proteins and RNA molecules that maintain latent infection are also responsible for the ability of this virus to transform host B-lymphocytes.
• Infectious mononucleosis, caused by acute EBV infection, classically presents with fever, pharyngitis and cervical lymphadenopathy.
• EBV is identified in several haematological malignancies, including Burkitt lymphoma and classical Hodgkin lymphoma.

Keeping LDL-C levels lower throughout life can help substantially reduce CVD risk.¹ GPs play an essential role in identifying patients at risk of CVD and managing their treatment.² This includes prescribing lipid-lowering medicines for people at high risk of CVD.³ Although for most patients, elevated lipids can be assessed and managed effectively by GPs, there are some groups of patients who may benefit from referral to a specialist.⁴ These include patients whose total cholesterol is more than 7.5mmol/L, patients who fail to show an effective response to second-line treatment and those with familial hypercholesterolaemia.⁴