- Epstein-Barr virus (EBV) is a human herpesvirus that persists lifelong in host B-lymphocytes in a ‘latent’ state.
- The viral proteins and RNA molecules that maintain latent infection are also responsible for the ability of this virus to transform host B-lymphocytes.
- Infectious mononucleosis, caused by acute EBV infection, classically presents with fever, pharyngitis and cervical lymphadenopathy.
- EBV is identified in several haematological malignancies, including Burkitt lymphoma and classical Hodgkin lymphoma.
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Keeping LDL-C levels lower throughout life can help substantially reduce CVD risk.1 GPs play an essential role in identifying patients at risk of CVD and managing their treatment.2 This includes prescribing lipid-lowering medicines for people at high risk of CVD.3 Although for most patients, elevated lipids can be assessed and managed effectively by GPs, there are some groups of patients who may benefit from referral to a specialist.4 These include patients whose total cholesterol is more than 7.5mmol/L, patients who fail to show an effective response to second-line treatment and those with familial hypercholesterolaemia.4