Is an SNRI effective in knee OA?

A random comment offers the chance to determine duloxetine’s efficacy

Fatima, a 59-year-old woman living with painful knee osteoarthritis, was brought in by her daughter, a pharmacy assistant who is one of my regular patients.

During the consultation, the potential analgesic role of duloxetine, a serotonin and noradrenaline reuptake inhibitor antidepressant, came up.