AF patients on NOACs have higher stroke rate

A study finds a 29% increased risk with NOACs in the back-and-forth debate over anticoagulants

Patients with atrial fibrillation (AF) taking non-vitamin K antagonist oral anti­coagulants (NOACs) may be at a higher risk of ischaemic stroke than those on warfarin, a large study suggests.

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Although at odds with previous research, the results suggest a need for more intensive monitoring of levels of anticoagulation among patients taking NOACS, the authors say.

The retrospective US study compared relative stroke incidence among 71,300 patients with AF on a NOAC and 59,500 patients with AF on warfarin.

Their records were held by a national hospital network database.

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