Antipsychotics for Alzheimer's don't boost need for BPH meds
Men with Alzheimer's disease who are on antipsychotics are not more likely to need medication to treat their benign prostatic hyperplasia, according to a new study.
Some antipsychotics exacerbate symptoms of benign prostatic hyperplasia (BPH) because of their anticholinergic effects, and are not recommended for men with the condition.
But whether antipsychotics increase the need for BPH medications in men with Alzheimer's disease has not previously been studied.
Finnish researchers used data from more than 4579 antipsychotic users and 4579 matched non-users, all with Alzheimer's disease, in the Medication and Alzheimer's disease (MEDALZ) study to investigate whether the use of antipsychotics is associated with an increased risk of initiating medication for BPH.
The number of men who started BPH medication after an Alzheimer's disease diagnosis was 7.4 per 100 person-years among