Aussie bisphosphonates-breast cancer discovery
Australian researchers have shown why bisphosphonates may benefit patients with tumours outside the skeleton, including breast cancer.
A study by Professor Mike Rogers, Dr Tri Phan and Dr Simon Junankar from Sydney’s Garvan Institute has used sophisticated imaging technology to revealthat the drugs attach to tiny calcifications in tumours in mice.
These calcium-drug complexes are then devoured by macrophages, immune cells that the cancer uses early in its development to conceal its existence.
Several clinical trials have