Australian cardiologist rejects warfarin advice

An Australian cardiologist has dismissed recommendations from US researchers to switch seemingly stable warfarin patients to novel oral anticoagulants.

The recommendations follow a US study of 3749 AF patients taking warfarin, which found that only 26% were stable in an initial six-month monitoring period.

Stable was defined as having 80% or more INR readings within the range of 2.0-3.0.

Subsequently, only 34% of these patients remained stable, while 36% had at least one out-of-range INR value of less than 1.5 or more than 4.0 in the following year.

“This analysis suggests warfarin stability is difficult to predict and challenges the notion that patients who have done well taking warfarin should maintain taking warfarin,” they write.

However, Dr Stefan Buchholz (pictured), an associate cardiologist at HeartCare Sunshine Coast, said he had