Autism risk higher in boys due to genetics

Researchers from the University of Lausanne in Switzerland and the University of Washington in Seattle have discovered compelling evidence of a “female protective model”.

It proposes that females require more extreme genetic mutations than males to push them over the diagnostic threshold for neurodevelopmental disorder or autism spectrum disorder (ASD).

They analysed DNA samples from a cohort of 15,558 people with neurodevelopmental disorders, and another cohort of 762 families