The best way to screen for familial hypercholesterolaemia

And it’s not necessarily measuring LDL cholesterol

People who have close relative with hypercholesterolaemia should be given a DNA test as a matter of course, according to new UK guidelines.

DNA testing

The updated guidance from the National Institute for Health and Care Excellence (NICE) suggests all primary-care medical records be systematically examined to identify those at risk.

This includes patients who have a total cholesterol concentration greater than 7.5mmol/L if they are under 30 years old or 9.0mmol/L if they are aged 30.

The guideline also states that DNA testing — known as cascade testing — is the gold standard to