Call for caution on B12–folate tests

The continuing growth in vitamin B12 and folate testing needs to be reviewed because testing may be inappropriate and inaccurate, experts say.

Ordering of combined serum B12—folate tests has increased by 22% a year since 2000, but accurate diagnosis is hampered by the lack of a gold standard and inconsistent cut-off values for vitamin B12 and folate deficiencies, public health researchers wrote in the Medical Journal of Australia.

"The issue