Cannabinoids no good for advanced cancer pain: study

Active agents proved no better than placebo and had more adverse events

Cannabinoids cannot be recommended for chronic pain in adult patients with advanced cancer as they are no more effective than placebo, UK researchers say.


Their systematic review and meta-analysis showed no difference in pain scores between clinically relevant cannabinoids and placebo. But it did find a higher risk of adverse events with the active agents.

Six randomised controlled trials, including phase 2 and 3 studies, were included in the review. The meta-analysis included five