CBT-antidepressant combo cuts kids' migraine

Amitriptyline coupled with CBT can substantially improve rates of migraine attacks in children and adolescents, research shows.

A US trial has found that the antidepressant-psychotherapy combination substantially reduces the rate of headaches in paediatric patients with frequent migraines.

More than 130 participants aged 10-17 who experienced an average of 21 migraines per month were randomised to receive amitriptyline (1mg/kg/day), and either CBT or headache education.

The CBT intervention involved training in relaxation and coping with pain.

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