Change of tack on penicillin allergy

Most patients who have a history of penicillin allergy are not really allergic and should be reevaluated before they are prescribed a replacement drug regimen, argue Australian infectious disease experts.

The vast majority of these patients will turn out not to be allergic and can be safely treated with penicillin, they say, adding that true penicillin allergy is rare, affecting only 1% of the general population.

Writing in JAMA, they say that retesting those thought to be allergic will help avoid the use of alternative antibiotics that are  “less effective, more toxic and expensive, and that