Common drug linked to depression

Doctors are being warned to be alert for signs of depressive disorder in women being treated for overactive bladder.

A study of almost 3000 Taiwanese women with the condition reveals that those prescribed antimuscarinics are 38% more likely to be diagnosed with depressive disorder within three years, compared with those not on the treatment.

While antimuscarinic drugs — including oxybutynin, tolterodine and trospium — are the mainstay of overactive bladder, with large studies showing good efficacy, they can produce varying degrees of adverse effects, such as dry mouth, blurred vision, confusion,