Confusion reigns over statin dosing

Pharmacologists have raised concerns about a wide variation in statin dosing in Australia, suggesting the trend reflects a paucity of evidence-based guidelines.

Excessive dosing increases side effects and insufficient dosing can cause avoidable cardiovascular events, say the West Australian pharmacologists who have conducted an audit that shows a 64-fold dosing variation.

This inconsistency is at odds with the more uniform doses of other drugs used