Dabigatran results ‘enormously reassuring’

A landmark anticoagulant study in a real-world setting has found dabigatran significantly reduces risk of ischaemic stroke, intracranial haemorrhage, MI and death compared with warfarin, although it may lead to greater GI bleeding in the elderly.

Published in the journal Circulation, the US study looked at over 134,000 elderly patients taking either dabigatran or warfarin for the treatment of non-valvular atrial fibrillation (AF) from 2010 to 2012.

It found that compared with those on warfarin, dabigatran patients had a 20% lower risk of