Doctors' last-ditch drug choice saves patient with status asthmaticus

The patient had already been given prednisone for eight days

An allergy drug  can be an effective rescue therapy for refractory status asthmaticus related to pollen allergy, a case report suggests.

The drug omalizumab appeared to be a game-changer after all other treatments failed to produce a sufficient response in a male patient, said Dr Katrin Milger, from Ludwig Maximilian University of Munich in the Annals of Internal Medicine.

"This is remarkable, because immunosuppressive treatment with prednisone had already been given for eight days," Dr Milger said.

The case involved a 41-year-old patient with a history of asthma with pollen allergy who developed severe dyspnoea while working at an outside construction site.

He was intubated at the construction site and hospitalised.

His initial arterial blood gas analysis during mechanical ventilation revealed severe hypercapnic respiratory failure that