Experts slam ‘flawed’ study claiming Tamiflu cut death risk by a quarter
The research, conducted by independent epidemiologists but financed by the manufacturers, has come under fire from an Australian expert involved in the Cochrane Collaboration, which has previously found no evidence that Tamiflu prevented complications such as pneumonia in healthy people.
Professor Chris Del Mar from the Centre for Research in Evidence-Based Practice at Bond University on the Gold Coast said the idea that the observational study, published in the journal Lancet Respiratory Medicine, could trump the meta-analysis conducted by the Cochrane Review was "crazy".
“To argue that it is unethical to do an randomised controlled trial is debatable. If there is real uncertainty then we need an RCT,” Professor Del Mar told MO.
The researchers collated data from 78 studies involving more than 29,000 patients in 38 different countries who were admitted to hospital during the H1N1 pandemic.
It found that