Fatty liver disease - who is at most risk of cancer?

Study helps identify who needs regular monitoring

People with advanced cases of non-alcoholic fatty liver disease (NAFLD) may need to be monitored for liver cancer, a large US study suggests.

Fatty liver disease is known to be linked with a higher risk of hepatocellular carcinoma. But it hasn't been clear whether some patients are more at risk than others.

The new study shows that when NAFLD progresses to cirrhosis, the risk for hepatocellular carcinoma is dramatically higher.

The findings suggest that people with NAFLD and cirrhosis should be monitored for hepatocellular carcinoma, the authors write in Gastroenterology.

Among people with less severe NAFLD, the risk of liver cancer was not particularly high.

Therefore, the need for regular monitoring did not apply to everyone with NAFLD, Dr Talal Adhami said. Dr Adhami, a member of the American Liver Foundation's National Medical Advisory Committee, was not involved in the