Hot flushes in menopause linked to pregnancy disorders
Women who develop hypertension during pregnancy or gestational diabetes mellitus (GDM) may be more likely to have a greater number of vasomotor symptoms during their menopausal transition, according to new research.
Hot flushes are associated with vascular endothelial dysfunction, as are hypertensive disorders of pregnancy (HDP) and GDM.
Given the similar pathophysiology, US researchers have theorised that women with a history of HDP or GDM could experience a greater burden of hot flushes during menopause.
They analysed data on 2249 women from the longitudinal Study of Women's Health Across the Nation.
The women were aged around 61 at the time that they answered questions on pregnancy history.
The study found that about 18% of the women were nulliparous, 73% parous without HDP/GDM and 9% were parous with HDP/GDM.
Of the women with HDP/GDM, 85% had HDP only,