How to tackle antipsychotic-induced weight gain

Antipsychotic-associated obesity can be avoided with diabetes drugs such as liraglutide, studies show. But psychiatrist Associate Professor Dan Siskind says it’s early days for prophylaxis.

Australian Doctor: How effective are glucagon-like peptide-1 (GLP-1) receptor agonists such as liraglutide in managing antipsychotic-induced weight gain?

Professor Siskind: Olanzapine or clozapine causes GLP-1 dysregulation, so we suspect the GLP-1 receptor agonists exogenously provided are able to modify the