Increased fracture risk with suppressed TSH

Patients with osteoporosis should be screened for thyroid disease, endocrinologists say after a large multinational study found subclinical hyperthyroidism is associated with increased fracture risk.

The risks are highest in those with suppressed thyroid stimulating hormone (TSH) (<0.1mIU/L) and those with endogenous subclinical hyperthyroidism, according to the meta-analysis of 13 prospective studies, including from Australia, covering 70,000 asymptomatic individuals.

“The take-home message would be that patients with osteoporosis should have their thyroid function checked,” says Clinical