A large study confirms link between PPIs and pneumonia

The primary care study is the first to examine the long-term risk of treatment

PPIs are linked to a heightened risk of pneumonia even two years after initiation in older people, a large study suggests.

PPIs and pneumonia

The risk of pneumonia among patients aged 60 or over was threefold higher in the second year after starting on PPIs compared with the two years before starting the drugs, the UK study showed.

Previous studies were at odds over whether PPIs increased the risk of pneumonia, with some suggesting they did so from 1-12 months, the authors from UNSW and the University of Exeter said.

The new study, based on more than 75,000 records of general