Long-term follow-up backs safety of HRT

18-year follow-up finds no increase in mortality.

There is "compelling and reassuring" mortality data to back the safety of HRT, according to a reanalysis of the controversial Women's Health Initiative study, say researchers.


While there has been much debate about HRT's impact on individual disease outcomes, a study in JAMA shows that short-term use is not linked to an increase in all-cause or disease-specific mortality.

Harvard Medical School researchers assessed mortality outcomes in 27,000 women who used HRT for an average of 5.6 years, and found no difference