Medicines update

Denosumab sparks dental concerns

Patients taking the bone anti-resorptive agent denosumab should be warned about the danger of dental surgery, say Perth oral health specialists.

Even minor dental manipulation is a risk factor for denosumab-associated osteonecrosis of the jaws (DONJ), they write in the Australian Dental Journal.

“The importance of avoiding interventional dental treatment until denosumab has been withdrawn for six months cannot be overstated,” they