Moody teens still a mystery

Tears and temper tantrums may be the curse of female adolescence but attributing mood swings to pubertal hormone changes is not supported by evidence, report Australian researchers.

Their systematic review was unable to find evidence confirming the primary puberty hormone estradiol is to blame.

“Three longitudinal and several cross-sectional studies indicate potential association between estradiol and certain mood or affective states, especially depression and