New evidence links benzos to Alzheimer’s

Benzodiazepines are associated with an increased risk of Alzheimer’s disease, according to international research that suggests long-acting formulations are particularly problematic.

The risk is so high that the researchers urge doctors to carefully evaluate the risks and benefits before prescribing these drugs.

The case-control study based on almost 9,000 elderly people shows the risk is increased by up to 51% among those who use benzodiazepines for more than three months.

Adjustment for symptoms that might indicate the start of dementia, such as anxiety, depression or sleep disorders, did not meaningfully alter the results.

While the deleterious effects of benzodiazepines on memory are well documented, this study by French and Canadian researchers shows there is a dose-effect relation between