New marker better predicts metastasis

Sentinel node spread is known to be a crucial factor for melanoma outcomes and the accuracy of identifying metastatic cells in the sentinel node can be improved with the use of immunohistochemistry.

German researchers analysed 1834 sentinel nodes from 1027 patients with ultrasound negative melanoma who underwent SNB using histopathology, immunohistochemistry and quantitative immunocytology. For the immunocytology, they recorded the number of disseminated cancer cells per one million lymph node cells (DCCD) after staining for a