Non-SSRI antidepressants raise risk of GDM

Greatest risks seen with tricyclic amitriptyline and venlafaxine, study reports

Women taking antidepressants other than SSRIs during pregnancy have a heightened risk of developing gestational diabetes, an observational study shows.

pregnant woman

The Canadian researchers say their study, involving more than 20,000 women with gestational diabetes (GDM), is the first to gauge risk from different classes of antidepressant and duration of use.

They found a 19% increased risk for use of any antidepressant in pregnancy compared with no antidepressant use, but noted that the potential for adverse outcomes needed to be