NSAID triple combo raises kidney risk

Prescribing a ‘triple whammy' of an NSAID on top of two antihypertensive drugs increases patients' risk of acute kidney injury by almost one-third, research finds.

The study of half a million hypertensive patients in UK general practice found that combining an NSAID with two antihypertensives increased the risk of kidney injury requiring hospitalisation by 31%, over an average of six years.

The risk was highest during the first 30 days of triple therapy, when