Paracetamol in utero makes males less 'manly'

Paracetamol taken in pregnancy may affect male sexual development and result in reduced masculation of the adult brain, according to a “highly important” study on fetal exposure to the drug.

The study on mice notes that male pups exposed to paracetamol in utero are ultimately less aggressive and less likely to mate with females, say the Danish researchers.

They also note a decreased number of neurons in brain areas connected to sexual behaviour.

Exposure to paracetamol in the mice was at levels comparable to maximum doses regarded as safe for pregnant women.

The authors said