Phlebotomy ineffective for fatty liver disease

Phlebotomy will be abandoned as a treatment for non-alcoholic fatty liver disease (NAFLD) because reducing ferritin levels has no impact on progression of the disease, liver specialists say.

Although iron is implicated in the pathogenesis of liver injury in people with NAFLD, venesection has no effect on progression of liver injury or other complications, a prospective trial conducted at the Sir Charles Gairdner Hospital in WA has shown.

The study of 74 people with NAFLD found no difference in outcomes such as hepatic steatosis, liver injury (ALT levels) or insulin resistance among patients randomised to