Prescribe PPIs for elderly aspirin users: study

Older patients taking low-dose aspirin should be co-prescribed a PPI because they have a very high risk of serious and fatal gastrointestinal bleeds, new research shows.

A 10-year study of more than 3000 UK patients treated with aspirin for secondary prevention after a heart attack or stroke has found a seven times higher risk of a fatal upper gastrointestinal bleed and a fourfold higher risk of a major non-fatal upper gastrointestinal bleed in older patients compared with those under the age of 75.

The findings change the balance of risk and benefit for low-dose aspirin for