Questions raised over familial cholesterolaemia and CVD risk

Study shows hospitalisations for CVD and ischaemic stroke no higher in this group

Patients with familial cholesterolaemia may not be at increased risk of cerebrovascular disease (CVD) and ischaemic stroke after all, according to a registry study from Norway.

Earlier studies on the potential link have produced mixed findings, write Dr Anders Hovland of the University of Tromsoe and colleagues in the journal Stroke.

"Our results raise new questions on the specific role of LDL cholesterol in cerebrovascular disease and ischaemic stroke," they note.

The researchers linked people with familial cholesterolaemia to the nationwide database of CVD hospitalisations between 2001 and 2009.

Among people with familial cholesterolaemia, 46 out of 3144 were hospitalised for CVD and 26 out of 3166 were hospitalised with ischaemic stroke

Neither result suggested an increased risk compared with the general population,

However, women with prior coronary

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