Rheumatologist urges calm after front-page news of OA 'breakthrough'

The front-page news shouldn't be news at all, says Professor David Hunter.

A decades-old drug is being touted as a potential cure for advanced osteoarthritis, but a leading rheumatologist warns against raising false hopes based on early case studies.

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Pentosan polysulfate sodium is a glycosaminoglycan with chondroprotective effects that has been lauded for producing dramatic relief of knee osteoarthritis.

Media coverage cited a case report of a 70-year-old woman with knee OA and bone marrow oedema lesions, who was treated with twice-weekly injections of the drug for three weeks.

In the case study released by the sponsor of the drug, Paradigm Biopharma, the woman

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