Scientists solve cannabis 'munchies' mystery

People who empty the refrigerator after smoking cannabis can blame their cravings on modified circuitry in the hypothalamus.

"We were able to see what drives the hunger brought about by cannabis and how that same mechanism that normally turns off feeding becomes a driver of eating," says Tamas Horvath of Yale University, who led the a mouse study on the subject.

His study published in the journal Nature shows how cannabinoids affect pro-opiomelanocortin (POMC) neurons, interfering with satiety signals.