Seminal fluid markers more accurate than PSA

Researchers from the Freemasons Foundation Centre for Men's Health at the University of Adelaide tested semen samples from 60 men for a range of ribonucleic acid (RNA) molecules or microRNAs that are known to be increased in prostate tumours. 

The men tested were already considered to be candidates for prostate cancer according to their prostate-specific-antigen (PSA) test results. Biopsy later confirmed that 32 of the men had cancer and 28 did not.

University of Adelaide research fellow and lead author of the study, Dr Luke Selth said that the results of the study indicated that, in the men tested, each of the micro-RNAs alone was a better predictor of a cancer diagnosis via biopsy than the PSA test. In addition, several of the micro-RNAs, when added to the PSA test results, were a better predictor of the presence of cancer than the PSA test alone.

Dr Selth said the results were promising both in terms of detecting the presence of cancer and