A single voice for PCOS
DIAGNOSIS of polycystic ovary syndrome (PCOS), based on the 2003 Rotterdam criteria, requires two of three features: oligo or amenorrhoea, clinical or biochemical hyperandrogenism, and polycystic ovaries on ultrasound,1,2 with exclusion of secondary causes.
PCOS has recently been shown to affect 12–18% of women depending on the population studied and diagnostic criteria used, highlighting that PCOS is of clinical and public health importance,3 with considerable health and economic costs.
PCOS can present with features that include:
• reproductive (hyperandrogenism, hirsutism, anovulation, infertility)
• metabolic (insulin resistance, prediabetes, type 2 diabetes, adverse cardiovascular risk profiles)
• psychological features (anxiety and depression).4
There is considerable heterogeneity in clinical presentation, which also varies