Sixth case of HIV in patient taking PrEP

The US patient reported good adherence to PrEP in the 'extremely rare' case

The sixth known case of HIV transmission in a patient with high adherence to pre-exposure prophylaxis (PrEP) has been reported in the US.

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In a detailed case report published in the Lancet HIV, a 21-year-old Latino man in San Francisco tested positive to a strain of the virus that was resistant to emtricitabine – one of the two main drugs in PrEP – 13 months after treatment initiation.

The patient reported good adherence to PrEP and tested negative for HIV at all his regular follow-up visits until month 13, but throughout that period he