Sleep apnoea linked to elevated lipids

CVD risk factors including hyperlipidaema need to be carefully managed in OSA

Patients with obstructive sleep apnoea (OSA) are also likely to have dyslipidaemia, European research suggests.

OSA is an independent predictor of higher total cholesterol and LDL, elevated triglycerides and lower HDL, according to the cross-sectional analysis of more than 8000 sleep centre patients, published in Respirology.

Total cholesterol concentrations also gradually rise with increasing OSA severity, they found. 

"Our data clearly suggest that sleep apnoea may have a negative impact on lipid levels, which may in part explain the association between sleep apnoea and increased risk for cardiovascular disease," said lead researcher Dr Ludger Grote, from Sweden’s Gothenburg University.

“Patients with sleep apnoea, therefore, need careful management of all cardiovascular risk factors, including hyperlipidaema.”

Nearly 8600 study participants, mean age 50, were enrolled in the