Statin use in Indigenous patients risky

Statin use in Indigenous patients may be associated with high rates of serious and fatal myotoxicity, Adelaide researchers have warned.

In a newly published observational case series, clinicians from the Royal Adelaide Hospital and University of Adelaide have identified 15 cases of serious myotoxicity in Aboriginal or Torres Strait Islanders, which they say may be an underestimate of the true scale of the problem.

The reports include three deaths and two cases where patients with reactions to statins had permanent severe disability.

Writing in the Internal Medicine Journal this month, the researchers said painless weakness was the most common presentation of statin myotoxicity.

Drug interactions, such as with gemfibrozil, were involved in seven cases.

Describing features from the case