Study demystifies link between cholesterol and dementia
Scientists have long known that hypercholesterolaemia in mid-life is a risk factor for dementia, but until now they didn’t know why.
A new study by a team from the University of Cambridge has found that the presence of cholesterol in cell membranes can act as a trigger for the aggregation of amyloid beta.
This eventually leads to the formation of amyloid plaques, in a toxic chain reaction that leads to the death of brain cells.
In fact, the researchers found that cholesterol speeds up the aggregation of amyloid beta by a factor of 20.
So what, if anything, can be