Teens at risk with high-dose SSRIs

Starting children and young adults on high-dose antidepressants doubles their risk of suicidal behaviour compared with initiating lower-dose therapy, a large study finds.

The research of more than 163, 000 Americans initiated on SSRIs found that those in the 10 to 24-year old age bracket who were commenced on double the normal dose of the drugs had a two-fold increase in the risk of deliberate self-harm.

This would account for one additional case of deliberate self-harm for every 136 people in that