Three antihypertensives that affect the mind

Three commonly prescribed blood pressure medications could affect people’s moods, UK cardiology researchers warn.

But only two are likely to be detrimental to mental health.

The study of more than half a million people compared four common classes of antihypertensive drugs including angiotensin antagonists, beta blockers, calcium channel blockers and thiazide diuretics.

Calcium antagonists and ß-blockers increased risk for mood disorders such as depression and bipolar disorder, while angiotensin-converting enzyme (ACE) inhibitors and angiotensin-receptor blockers (ARBs) lessened the risk.

Thiazide diuretics did not seem to impact on mood either way.

More specifically,  the study found that:

  • Patients on ß-blockers and calcium antagonists were at two-fold increased risk of hospital admission for