Treatment tables turn for otitis media

Antibiotics should be given for 10 rather than five days if used for acute otitis media in children under two, a major study has shown.

Although many guidelines recommend a five-day course of antibiotics to minimise bacterial resistance, a randomised trial has shown that this has a higher failure rate than a 10-day course, without reducing resistance rates.

The findings come from a prospective randomised trial of amoxicillin-clavulanate treatment in 520 US children aged six months to two years with acute otitis media (AOM), published in the New England Journal of Medicine.

In the study, children