Two therapies better than one for severe pain

A combination of nortriptyline and morphine works better than either drug alone in managing pain, say Canadian researchers.

When used together in a study, the opioid and tricyclic antidepressant relieved chronic neuropathic pain in 87% of patients, a significantly better result than achieved with either drug alone.

“Current neuropathic treatments are ineffective or intolerable for many sufferers so this new evidence is important news,” says lead author Professor Ian Gilron the director of