Ulcerative colitis

Dr Suresh Sivanesan, MBBS, FRACP, PhD (Lon)
Director of Clinical Research, Colorectal Medicine and Genetics, Royal Melbourne Hospital.

INTRODUCTION
ULCERATIVE colitis (UC) is a form of inflammatory bowel disease. As the name suggests, the disease affects the colon, and despite the volume of research in this area, the aetiology of this condition remains unknown. It is a chronic condition with periods of remission interrupted by flares of the disease.

A genetic component to UC has always been

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