Warning issued over NOACs in antiphospholipid syndrome

There is increased risk of thrombotic events with the drugs in some patients, says TGA

Regulators are warning about the use of non-vitamin K antagonist oral anticoagulants in patients with antiphospholipid syndrome.

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Product information is being updated to include new data about an increased risk of thrombotic events in patients diagnosed with the syndrome, the TGA says in a safety alert.

The non-vitamin K antagonist oral anticoagulants (NOACs) marketed in Australia are apixaban (Eliquis), dabigatran etexilate (Pradaxa) and rivaroxaban (Xarelto).

The warning comes after a trial showed an increase in the risk of recurrent thrombotic

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